Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026805 | 1.00 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7236400 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7236396 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7225935 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7160554 | 0.87 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7492463 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7491310 | 0.80 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7167530 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7163609 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7163491 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562810-B1 | Competitive AMPA/kainite antagonist properties making them useful in the treatment of diseases where inhibition of the AMPA/kainite receptors may a favorable effect | EGIS GYOGYSZERGYAR RT. (HU) | 2003-05-13 | — | — | US | claimed |
| WO-2000053166-A2 | USE OF CONDENSED 2,3-BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF DISEASES RELATED TO THE INHIBITION OF LIPID PEROXIDATION | EGIS Gyógyszergyár Rt. (HU) | 2000-09-14 | — | — | WO | disclosed |