SCHEMBL716552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL719968	0.91	NPC1 (0.38)	NPC1RAB9ATEAD4HCRTR1VKORC1
	SCHEMBL717568	0.90	TEAD4 (0.39)	TEAD4
	SCHEMBL720639	0.90	TEAD4 (0.37)	NPC1RAB9ATEAD4TP53MAPT
	SCHEMBL718671	0.89	MAOB (0.38)	TEAD4CA9TP53MAPT
	SCHEMBL3403389	0.88	NPC1 (0.36)	NPC1RAB9ATEAD4
	SCHEMBL3400805	0.88	MAPT (0.37)	NPC1RAB9ATEAD4TP53MAPT
	SCHEMBL719224	0.88	NPC1 (0.44)	NPC1RAB9ATEAD4TP53MAPT
	SCHEMBL719424	0.88	TEAD4 (0.37)	TEAD4CA12CA9TP53MAPT
	SCHEMBL717558	0.88	MAPT (0.37)	TEAD4TP53MAPTALDH1A1PKM
	SCHEMBL3399101	0.87	TEAD4 (0.36)	TEAD4HDAC6ABL1RIN1RCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.