Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.50 |
| ▸ | PPARA | Q07869 | 15/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052195 | 0.92 | FFAR1 (0.49) | PPARGPPARA | |
| SCHEMBL7494754 | 0.91 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL7165952 | 0.90 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL7162684 | 0.90 | FFAR1 (0.49) | PPARGPPARA | |
| SCHEMBL7162962 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL7162078 | 0.88 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL7164860 | 0.86 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL8794374 | 0.84 | FFAR1 (0.60) | PPARGPPARAPPARD | |
| SCHEMBL6583863 | 0.83 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL7909696 | 0.82 | PPARG (0.60) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552058-B1 | For therapy of diabetes or hyperlipidemia | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-22 | — | — | US | claimed |
| EP-0612743-A1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | claimed |