Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | MPC2 | O95563 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088179 | 0.94 | FFAR1 (0.56) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6184625 | 0.88 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6184607 | 0.86 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5395861 | 0.81 | FFAR1 (0.63) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6184178 | 0.80 | FFAR1 (0.53) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5390735 | 0.79 | FFAR1 (0.56) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL4321481 | 0.79 | FFAR1 (0.62) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL7090099 | 0.79 | FFAR1 (0.49) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6526188 | 0.78 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL7522025 | 0.78 | FFAR1 (0.62) | FFAR1PPARGMPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |