Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166902 | 0.95 | SPPL2A (0.48) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7169933 | 0.94 | SPPL2A (0.47) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7162729 | 0.94 | SPPL2A (0.47) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7167033 | 0.94 | SPPL2A (0.47) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7166686 | 0.93 | SPPL2A (0.46) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7169067 | 0.93 | SPPL2A (0.51) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL14189497 | 0.93 | SPPL2A (0.48) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7168391 | 0.92 | SPPL2A (0.48) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL14189509 | 0.92 | SPPL2A (0.47) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL7165353 | 0.91 | SPPL2A (0.49) | SPPL2AMLNRABCB11LMNACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562848-B1 | For treating HIV infection, comprising: administering claimed compound with at least one compound selected from the group consisting of HIV reverse transcriptase inhibitors and HIV protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562848-B1 | For treating HIV infection, comprising: administering claimed compound with at least one compound selected from the group consisting of HIV reverse transcriptase inhibitors and HIV protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-13 | — | — | US | disclosed |