Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167154 | 1.00 | GRIA1 (0.52) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7921736 | 0.85 | GRIA1 (0.46) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| Water SCHEMBL7159005 | 0.84 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| Water SCHEMBL7159011 | 0.84 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7159018 | 0.83 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7159013 | 0.83 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7168351 | 0.83 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7164183 | 0.81 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7164181 | 0.81 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7160399 | 0.79 | GRIA1 (0.52) | GRIA1GRIA3GRIA2GRIA4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934286-B1 | 3-ALKOXYISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | LUNDBECK & CO AS H (DK) | 2003-01-08 | — | — | EP | disclosed |
| US-6200999-B1 | ALZHEIMER*S, HUNTINGTON*S, AND PARKINSON*S DISEASE; ANTIEPILEPTIC, ANALGESIC, ANXIOLYTIC, ANTIISCHEMIC AND ANTIDEPRESSANT AGENTS; NMDA AND AMPA RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2001-03-13 | — | — | US | disclosed |