Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786115 | 1.00 | HRH3 (0.49) | HRH3KCNH2 | |
| SCHEMBL13865071 | 0.87 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL12990262 | 0.82 | HRH3 (0.55) | HRH3 | |
| SCHEMBL13865040 | 0.80 | HRH3 (0.55) | HRH3KCNH2 | |
| SCHEMBL13863633 | 0.80 | HRH3 (0.55) | HRH3KCNH2 | |
| SCHEMBL2784907 | 0.76 | HRH3 (0.53) | HRH3 | |
| SCHEMBL2787630 | 0.74 | HRH3 (0.49) | HRH3 | |
| SCHEMBL7194869 | 0.73 | HRH3 (0.47) | HRH3 | |
| SCHEMBL2784905 | 0.73 | HRH3 (0.47) | HRH3 | |
| SCHEMBL2786102 | 0.73 | HRH3 (0.46) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370546-A2 | NOVEL AMINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | Abbott Laboratories (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002074758-A2 | NOVEL AMINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LABORATORIES (US) | 2002-09-26 | — | — | WO | disclosed |