Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167830 | 1.00 | HIF1A (0.53) | HIF1ATSHRSMN1; SMN2CD274CAPN1 | |
| SCHEMBL7168758 | 0.91 | HIF1A (0.59) | HIF1ACAPN1 | |
| SCHEMBL7168763 | 0.91 | HIF1A (0.59) | HIF1ACAPN1 | |
| SCHEMBL9894780 | 0.90 | HIF1A (0.53) | HIF1ACD274 | |
| SCHEMBL9894776 | 0.90 | HIF1A (0.53) | HIF1ACD274 | |
| SCHEMBL9894778 | 0.90 | HIF1A (0.53) | HIF1ACD274 | |
| SCHEMBL9895099 | 0.90 | HIF1A (0.66) | HIF1A | |
| SCHEMBL9895094 | 0.90 | HIF1A (0.66) | HIF1A | |
| SCHEMBL9895092 | 0.90 | HIF1A (0.66) | HIF1A | |
| SCHEMBL7171493 | 0.87 | HIF1A (0.65) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653258-B1 | Pyridinyl-substituted- methyl 3-methoxy-2-phenylacrylate derivatives; agricultural miticides and nematocides | SYNGENTA LIMITED (GB) | 2003-11-25 | — | — | US | disclosed |
| US-5438059-A | Derivatives of propenoic acid; stereoisomers; applying to plants | ZENECA LIMITED (GB) | 1995-08-01 | — | — | US | disclosed |
| US-5021581-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |