Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168977 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL7167271 | 1.00 | EPHX1 (0.44) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL2880168 | 0.98 | — | — | |
| SCHEMBL5652517 | 0.90 | — | — | |
| SCHEMBL106108 | 0.79 | — | — | |
| SCHEMBL8819253 | 0.77 | — | — | |
| SCHEMBL1519038 | 0.76 | CA12 (0.40) | CA1CA2TSHRCASP2 | |
| SCHEMBL23270896 | 0.76 | EPHX1 (0.61) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL8416435 | 0.76 | EPHX1 (0.61) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL1795309 | 0.76 | EPHX1 (0.61) | EPHX1ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569449-B1 | For treatment of eating disorders, narcotic dependence and alcoholism. | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2003-05-27 | — | — | US | claimed |
| US-6569449-B1 | For treatment of eating disorders, narcotic dependence and alcoholism. | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2003-05-27 | — | — | US | disclosed |