Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | THPO | P40225 | 2/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459497 | 0.85 | SLC6A4 (0.65) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL15486903 | 0.85 | SLC6A2 (0.73) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL5487930 | 0.84 | PTGS1 (0.71) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL7172308 | 0.84 | HTR2A (0.54) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL7168190 | 0.82 | SLC6A2 (0.67) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL15486794 | 0.79 | SLC6A2 (0.74) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL14698933 | 0.79 | SLC6A2 (0.65) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL14707081 | 0.79 | SLC6A2 (0.65) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL15908354 | 0.79 | SLC6A4 (0.67) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 | |
| SCHEMBL14698725 | 0.79 | SLC6A2 (0.65) | SLC6A2LMNACYP3A4SLC6A4SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |