SCHEMBL7168347

SCHEMBL7168347

COc1ccc(C(=O)COc2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.71
NPC1 O15118 4/20 0.71
RAB9A P51151 4/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
ALDH1A1 P00352 2/20 0.66
HTT P42858 1/20 0.66
HSD17B10 Q99714 1/20 0.66
LMNA P02545 1/20 0.65
POLB P06746 1/20 0.62
BLM P54132 1/20 0.62
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6181838 0.95 NPC1 (0.73) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL21100591 0.93 MAPT (0.73) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31357491 0.92 MAPT (0.78) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
Methoxymethane SCHEMBL27278268 0.87 MAPT (0.73) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL6746981 0.87 POLB (0.68) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31357499 0.87 POLB (0.68) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31357494 0.86 MAPT (0.70) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL10486772 0.86 MAPT (0.66) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL1068092 0.85 MAPT (0.69) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL9786970 0.85 MAPT (0.74) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116212919-B CdS/g-C3N4Nanosheet composite material and preparation method and application thereof 广西民族大学 2024-08-27 CN claimed
CN-116159578-A Iron catalyst for catalyzing oxidative cleavage of lignin model to produce phenol and ester and application thereof 天津理工大学 2023-05-26 CN claimed
CN-115697053-A Biocide composition 巴斯夫欧洲公司 2023-02-03 CN claimed
CN-118724726-A Method for converting lignin and model compound thereof into primary benzylamine and phenolic compound 中国科学院化学研究所 2024-10-01 CN disclosed
CN-116212919-B CdS/g-C3N4Nanosheet composite material and preparation method and application thereof 广西民族大学 2024-08-27 CN disclosed
CN-118255649-A Samarium diiodide mediated lignin beta-O-4 ketone model compound free radical cleavage 浙江大学 2024-06-28 CN disclosed
CN-116375641-A C3-phenoxy substituted quinoline compound and synthetic method and application thereof 杭州师范大学 2023-07-04 CN disclosed
CN-116212919-A CdS/g-C 3 N 4 Nanosheet composite material and preparation method and application thereof 广西民族大学 2023-06-06 CN disclosed
CN-116159578-A Iron catalyst for catalyzing oxidative cleavage of lignin model to produce phenol and ester and application thereof 天津理工大学 2023-05-26 CN disclosed
CN-109836311-B Method for controlling lignin model molecule fracture by amine at room temperature 中国科学院大连化学物理研究所 2022-05-06 CN disclosed
CN-114008832-A Method for extinguishing an electrochemical generator in the event of thermal runaway 原子能和替代能源委员会 2022-02-01 CN disclosed
US-6576643-B2 Compounds containing dibenzo(A,D)cycloheptene or dibenz(B,F)oxepine derivatives are useful for treating osteoporosis, cardiovascular diosrders, cancer and inflammation SMITHKLINE BEECHAM CORPORATION 2003-06-10 US disclosed
US-20020091264-A1 Vitronectin receptor antagonists SMITHKLINE BEECHAM CORPORATION 2002-07-11 US disclosed
EP-1025090-A4 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORP (US) 2000-11-08 EP disclosed
EP-1025090-A1 VITRONECTIN RECEPTOR ANTAGONISTS SmithKline Beecham Corporation (US) 2000-08-09 EP disclosed
WO-1999015508-A1 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091264-A1 Vitronectin receptor antagonists CALCR, ADGRF1, CALCRL MAPT 3004/4885NPC1 1061/4885RAB9A 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.