Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.68 |
| ▸ | DRD2 | P14416 | 5/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.68 |
| ▸ | HTR2C | P28335 | 5/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.68 |
| ▸ | HRH1 | P35367 | 5/20 | 0.68 |
| ▸ | DRD3 | P35462 | 5/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.68 |
| ▸ | HTR2B | P41595 | 4/20 | 0.68 |
| ▸ | MTOR | P42345 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195707 | 0.96 | HTR2A (0.70) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL7168298 | 0.87 | HTR2A (0.66) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL29485897 | 0.86 | HTR2A (0.68) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL22748895 | 0.86 | HTR2A (0.68) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL31256048 | 0.86 | HTR2A (0.68) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL31256054 | 0.86 | HTR2A (0.71) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL6963908 | 0.86 | HTR2A (0.71) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL22767581 | 0.85 | HTR2A (0.67) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL29485883 | 0.85 | HTR2A (0.67) | HTR2ASLC6A4DRD2ADRA2BADRA2C | |
| SCHEMBL14707047 | 0.84 | HTR2A (0.74) | HTR2ASLC6A4DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569849-B1 | N-Substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-05-27 | — | — | US | disclosed |
| EP-0934306-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015546-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |