Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 9/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875870 | 0.96 | PIK3CB (0.39) | PIK3CBSOS1PIK3CDPIK3CAPIK3R2 | |
| SCHEMBL715553 | 0.96 | PIK3CB (0.39) | PIK3CBSOS1PIK3CDPIK3CAPIK3R2 | |
| SCHEMBL715520 | 0.90 | PIK3CD (0.46) | PIK3CBSOS1PIK3CDPIK3CATSHR | |
| SCHEMBL717085 | 0.88 | ATR (0.38) | SOS1PIK3CDPIK3CACYP3A4PIK3CG | |
| SCHEMBL15875858 | 0.87 | PIK3CD (0.38) | PIK3CBSOS1PIK3CDPIK3R2 | |
| SCHEMBL714861 | 0.85 | PIK3CD (0.42) | PIK3CDPIK3R2 | |
| SCHEMBL17530835 | 0.85 | PIK3CA (0.39) | PIK3CBPIK3CDPIK3CAPIK3R2CYP1A2 | |
| SCHEMBL714860 | 0.85 | PIK3CD (0.42) | PIK3CDPIK3R2 | |
| SCHEMBL15875804 | 0.85 | PIK3CA (0.39) | PIK3CBPIK3CDPIK3CAPIK3R2CYP1A2 | |
| SCHEMBL715448 | 0.85 | SRC (0.40) | PIK3CDPIK3CAPIK3R2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | disclosed |
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | UCB PHARMA, S.A. (BE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | MAP3K15, PI4KA, MAP3K20 | PIK3CB 20/4885SOS1 1414/4885PIK3CD 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.