Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173457 | 1.00 | HPGD (0.53) | HPGDALDH1A1LMNACYP1A2PGR | |
| SCHEMBL2063868 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| Octabenzone SCHEMBL10805004 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| Octabenzone SCHEMBL27387 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| Octabenzone SCHEMBL10628531 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| SCHEMBL2805631 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| Octabenzone SCHEMBL8924481 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| SCHEMBL11679030 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| SCHEMBL38596 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR | |
| SCHEMBL31125307 | 0.90 | HPGD (0.64) | HPGDALDH1A1LMNACYP1A2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586519-B1 | Compounds which exhibit enhanced ultraviolet radiation absorption | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | claimed |
| US-6576797-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | claimed |
| US-6586519-B1 | Compounds which exhibit enhanced ultraviolet radiation absorption | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-6576797-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | disclosed |
| EP-0675108-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA GEIGY AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| EP-0675108-A1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA-GEIGY AG (CH) | 1995-10-04 | — | — | EP | disclosed |