Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.62 |
| ▸ | PDE4A | P27815 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174514 | 0.92 | KCNH2 (0.60) | KCNH2PDE4AKMT2APRKCI | |
| SCHEMBL7175570 | 0.92 | PDE4A (0.60) | KCNH2PDE4AKMT2APDE4BPDE4C | |
| SCHEMBL7175019 | 0.92 | KCNH2 (0.74) | KCNH2PDE4AKMT2APRKCI | |
| SCHEMBL7170288 | 0.92 | KCNH2 (0.59) | KCNH2PDE4AKMT2APRKCI | |
| SCHEMBL7175610 | 0.91 | KCNH2 (0.61) | KCNH2PDE4AKMT2A | |
| SCHEMBL7174788 | 0.90 | KCNH2 (0.58) | KCNH2PDE4AKMT2APRKCIPDE4B | |
| SCHEMBL7176329 | 0.90 | PDE4A (0.58) | KCNH2PDE4AKMT2APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7169936 | 0.88 | PDE4A (0.56) | KCNH2PDE4AKMT2APRKCIPDE4B | |
| SCHEMBL7171541 | 0.87 | KCNH2 (0.52) | KCNH2PDE4AKMT2APRKCIPDE4B | |
| Hydrochloric Acid SCHEMBL7174489 | 0.87 | KCNH2 (0.57) | KCNH2PDE4AKMT2APRKCIPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541480-B2 | Controlling cytokines | SUNTORY LIMITED (JP) | 2003-04-01 | — | — | US | disclosed |
| US-6297248-B1 | 1-aryl-1,8-naphthylidin-4-one derivative as type IV phosphodiesterase inhibitor | SUNTORY LIMITED (JP) | 2001-10-02 | — | — | US | disclosed |