Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.83 |
| ▸ | PPARG | P37231 | 16/20 | 0.83 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863004 | 0.91 | PPARA (1.00) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL29561793 | 0.91 | PPARA (1.00) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL7166687 | 0.89 | PPARA (0.81) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL7168930 | 0.82 | PPARA (0.77) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL7191771 | 0.81 | PPARA (0.69) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL7167912 | 0.81 | PPARA (0.72) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL7171462 | 0.79 | PPARA (0.67) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL4020042 | 0.78 | PPARA (0.86) | PPARAPPARG | |
| SCHEMBL7167773 | 0.78 | PPARA (0.81) | PPARAPPARGNR1H2NR1H3PPARD | |
| SCHEMBL4013005 | 0.77 | PPARA (0.85) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569879-B2 | Agonists of peroxisome proliferator activated receptor (PPAR) alpha and/or gamma; benzisoxazole compounds; e.g. ((5,7-dipropyl-3-trifluoromethyl-1,2-benzisoxazol-6-yl)oxy)acetic acid, methyl ester | MERCK & CO., INC. | 2003-05-27 | — | — | US | disclosed |
| US-20020173663-A1 | Aryloxyacetic acids for diabetes and lipid disorders | MERCK SHARP & DOHME CORP. | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173663-A1 | Aryloxyacetic acids for diabetes and lipid disorders | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885NR1H2 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.