Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045358 | 0.70 | ADORA2A (0.39) | HRH3 | |
| SCHEMBL691064 | 0.70 | HRH3 (0.48) | HRH3 | |
| SCHEMBL583517 | 0.61 | — | — | |
| SCHEMBL11691084 | 0.61 | ADORA2A (0.45) | HRH3 | |
| SCHEMBL23608703 | 0.60 | — | — | |
| SCHEMBL17045632 | 0.60 | NPC1 (0.46) | HRH3 | |
| SCHEMBL1292978 | 0.59 | ADORA2A (0.42) | — | |
| SCHEMBL14662929 | 0.59 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL3843249 | 0.57 | KDM4E (0.46) | — | |
| SCHEMBL690635 | 0.56 | ADORA2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421537-A1 | PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK | GlaxoSmithKline LLC (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010062578-A1 | PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC (US) | 2010-06-03 | — | — | WO | disclosed |