Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 1.00 |
| ▸ | CDC7 | O00311 | 8/20 | 0.71 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16042092 | 0.91 | BRD4 (0.82) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL2215320 | 0.86 | BRD4 (0.75) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16045418 | 0.85 | BRD4 (0.73) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16043468 | 0.84 | BRD4 (0.72) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16043465 | 0.84 | BRD4 (0.72) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16042278 | 0.84 | BRD4 (0.72) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16042670 | 0.84 | BRD4 (0.71) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL16042251 | 0.83 | BRD4 (0.71) | BRD4CDC7 | |
| SCHEMBL16042054 | 0.83 | BRD4 (0.70) | BRD4CDC7CCNA2CDK2CCNA1 | |
| SCHEMBL1450398 | 0.83 | BRD4 (0.71) | BRD4CDC7CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |