Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440412 | 0.94 | TSHR (0.34) | ALDH1A1GAAEPHX1TSHRPOLB | |
| SCHEMBL1326039 | 0.84 | PEPD (0.36) | ALDH1A1GAAPEPDPPM1BPTPN1 | |
| SCHEMBL2321591 | 0.83 | SNCA (0.42) | ALDH1A1TSHRPOLBMAPK1 | |
| SCHEMBL1326038 | 0.82 | TSHR (0.38) | ALDH1A1GAATSHRPOLBMAPK1 | |
| SCHEMBL27351320 | 0.81 | PEPD (0.42) | ALDH1A1GAAPEPDTSHRPOLB | |
| SCHEMBL25184942 | 0.80 | TSHR (0.42) | ALDH1A1PPM1BPTPN1PPP1CCTSHR | |
| SCHEMBL3290514 | 0.80 | EPHX1 (0.44) | ALDH1A1GAAEPHX1TSHRPOLB | |
| SCHEMBL1220674 | 0.78 | TP53 (0.43) | ALDH1A1GAAPEPDTSHRPOLB | |
| SCHEMBL28849182 | 0.75 | TP53 (0.58) | ALDH1A1PPM1BPTPN1PPP1CCACE | |
| SCHEMBL233752 | 0.74 | PPM1B (0.44) | ALDH1A1PPM1BPTPN1PPP1CCEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328560-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | Showa Denko K.K. (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002026843-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-04-04 | — | — | WO | disclosed |