SCHEMBL7174753

SCHEMBL7174753

CC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)N(C)C1CCCCC1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMBR P28336 20/20 0.74
GRPR P30550 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6181769 0.85 NMBR (1.00) NMBRGRPR
SCHEMBL6181007 0.84 NMBR (1.00) NMBRGRPR
SCHEMBL6250669 0.84 NMBR (1.00) NMBRGRPR
SCHEMBL6181026 0.83 NMBR (0.81) NMBRGRPR
SCHEMBL6181070 0.83 NMBR (0.86) NMBRGRPR
SCHEMBL6181687 0.81 NMBR (0.80) NMBRGRPR
SCHEMBL6178861 0.79 NMBR (1.00) NMBR
SCHEMBL6181867 0.79 NMBR (0.82) NMBRGRPR
SCHEMBL6180163 0.78 NMBR (0.96) NMBRGRPR
SCHEMBL6181023 0.78 NMBR (0.81) NMBRGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343498-A1 NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS Warner-Lambert Company LLC (US) 2003-09-17 EP disclosed
WO-2002049644-A1 NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed