Aniline

Aniline

SCHEMBL7175507

CC(C)=O.Nc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
PBRM1 Q86U86 1/20 0.48
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
HSD17B10 Q99714 3/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALDH1A1 P00352 4/20 0.45
NAPRT Q6XQN6 2/20 0.44
MAPT P10636 3/20 0.43
POLB P06746 1/20 0.43
PARP1 P09874 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CYP1B1 Q16678 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL27700711 0.95 TSHR (0.58) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL25370313 0.94 TSHR (0.65) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL1956601 0.94 TSHR (0.65) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL30678504 0.94 TSHR (0.65) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL27498974 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL27815330 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL28008359 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL28431695 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL27330317 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10
Aniline SCHEMBL27419313 0.92 TSHR (0.61) TSHRPBRM1CES2CES1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683110-A Preparation method of high-temperature-resistant silicon-modified alumina aerogel 中国人民解放军国防科技大学 2021-11-23 CN disclosed
CN-108483493-B Preparation method of high-strength zirconia aerogel 山东省科学院新材料研究所 2020-08-11 CN disclosed
CN-106378847-A Mould-proof and color fixing treatment agent for corn bran and using method of agent 安徽宏润工艺品有限公司 2017-02-08 CN disclosed
CN-103523829-B Preparation method of lumpy zirconia aerogel having high specific surface area UNIV TONGJI 2015-02-18 CN disclosed
CN-103523829-A Preparation method of lumpy zirconia aerogel having high specific surface area UNIV TONGJI 2014-01-22 CN disclosed
CN-102304037-A Method for extracting gossypol acetic acid from cottonseed meal in presence of solid acid catalyst MINGYUAN ZHU 2012-01-04 CN disclosed
CN-100395223-C Production process of medicinal gossypol acetic acid UNIV JINAN (CN) 2008-06-18 CN disclosed
CN-1966483-A Production process of medicinal gossypol acetic acid UNIV JINAN (CN) 2007-05-23 CN disclosed
EP-0743161-B1 Coextrusion process and article of manufacture UNION CARBIDE CHEM PLASTIC (US) 2003-03-19 EP disclosed
EP-0743161-A2 A process for extrusion UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-11-20 EP disclosed
US-5575965-A COEXTRUSION, ETHYLENE POLYMER, PEROXIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-11-19 US disclosed
US-5470866-A Method for the conversion of cephalomannine to taxol and for the preparation of n-acyl analogs of taxol VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 1995-11-28 US disclosed
US-5319112-A Hydrogenation, acylation, proctection, reaction with oxalyl chloride, then with diphenylcarbodiimide, deprotection VIRGNIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1994-06-07 US disclosed
EP-0147378-B1 LIQUID HYDROQUINOLINE-TYPE ANTIOXYDANTS MONSANTO COMPANY (US) 1987-05-06 EP disclosed
CN-85108568-A MAKING ACETIC ACID COTTON PHENOL BY ACETONE-WATER DILUTION TECHNOLOGY 1987-05-06 CN disclosed
EP-0147378-A1 Liquid hydroquinoline-type antioxydants MONSANTO COMPANY (US) 1985-07-03 EP disclosed
US-4033921-A ADHESIVES, COATINGS THE LUBRIZOL CORPORATION (US) 1977-07-05 US disclosed
US-4026856-A Adhesives prepared from alkaline reagents and polymers of water-soluble hydroxyalkylated and alkoxyalkylated compositions and the like derived from N-3-oxohydrocarbon-substituted acrylamides THE LUBRIZOL CORPORATION (US) 1977-05-31 US disclosed
US-3959224-A Water-soluble hydroxyalkylated and alkoxyalkylated compositions and the like derived from N-3-oxohydrocarbon-substituted acrylamides, and polymers thereof THE LUBRIZOL CORPORATION (US) 1976-05-25 US disclosed