Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176158 | 1.00 | ADORA2A (0.73) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4382557 | 0.92 | ADORA2A (0.70) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4382552 | 0.92 | ADORA2A (0.70) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4562392 | 0.92 | ADORA2A (0.70) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7073089 | 0.91 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4380793 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4560473 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6338095 | 0.89 | ADORA2A (0.71) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4380797 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4373572 | 0.88 | ADORA2A (0.80) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292604-A1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | Pfizer Limited (GB) | 2003-03-19 | — | — | EP | claimed |
| WO-2001094368-A1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-12-13 | — | — | WO | claimed |