Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL717779 | 1.00 | SLC7A5 (0.71) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL27571970 | 0.85 | SLC7A5 (0.88) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL15602719 | 0.85 | SLC7A5 (0.88) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL288203 | 0.84 | SLC7A5 (1.00) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL2785563 | 0.84 | SLC7A5 (1.00) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL41225 | 0.84 | SLC7A5 (1.00) | SLC7A5ALDH1A1MAPTPTGS1SLC1A3 | |
| Valine SCHEMBL31618928 | 0.84 | — | — | |
| Valine SCHEMBL43678 | 0.84 | — | — | |
| Valine SCHEMBL8516 | 0.84 | — | — | |
| Valine SCHEMBL8515 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124721-B2 | Peptides for modulating innate immunity | INIMEX PHARMACEUTICALS INC. (CA) | 2012-02-28 | — | — | US | disclosed |
| US-20110262485-A1 | STING (STIMULATOR OF INTERFERON GENES), A REGULATOR OF INNATE IMMUNE RESPONSES | UNIVERSITY OF MIAMI (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110195048-A1 | REGULATION OF LYMPHOCYTES AND USES THEREFOR | UNIVERSITY OF MIAMI | 2011-08-11 | — | — | US | disclosed |
| EP-2349315-A1 | REGULATION OF LYMPHOCYTES AND USES THEREFOR | University of Miami (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2324044-A2 | STING (STIMULATOR OF INTERFERON GENES), A REGULATOR OF INNATE IMMUNE RESPONSES | University of Miami (US) | 2011-05-25 | — | — | EP | disclosed |