Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114420 | 1.00 | TSHR (0.46) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL5160104 | 0.89 | NT5E (0.53) | NT5ETACR2PTPN2PTPN1PTPN6 | |
| SCHEMBL5160114 | 0.89 | NT5E (0.53) | NT5ETACR2PTPN2PTPN1PTPN6 | |
| SCHEMBL20287904 | 0.89 | TSHR (0.50) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL30039523 | 0.89 | TSHR (0.50) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL20870237 | 0.89 | TSHR (0.50) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL13380996 | 0.89 | TSHR (0.50) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL3136372 | 0.89 | TSHR (0.50) | TSHRLMNANT5EKMT2ATNF | |
| SCHEMBL21219187 | 0.88 | TSHR (0.59) | TSHRLMNAKMT2ATNFALDH1A1 | |
| SCHEMBL17502004 | 0.88 | TSHR (0.59) | TSHRLMNAKMT2ATNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579725-B1 | Compound of given formula; stable to reaction conditions but can also be cleaved; can use to attach building blocks useful in assembly of libraries of other small molecules | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-06-17 | — | — | US | disclosed |
| WO-2000052018-A9 | LINKERS FOR SYNTHESIS OF OLIGOSACCHARIDES ON SOLID SUPPORTS | MASSACHUSETTS INST TECHNOLOGY (US) | 2002-06-27 | — | — | WO | disclosed |