Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33509 | 0.76 | CYP3A4 (0.50) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Hydrochloric Acid SCHEMBL553599 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Fluoride SCHEMBL1502751 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Bromide SCHEMBL11815034 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Bromide SCHEMBL128888 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Water SCHEMBL35583 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Water SCHEMBL9259705 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| SCHEMBL15346025 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Iodide SCHEMBL1157672 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 | |
| Ammonia Solution, Strong SCHEMBL2462341 | 0.73 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CANOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610478-B1 | Delivering nucleic acids to bacterial cells. The method does not require manipulation of the bacteria and is therefore particularly suited to delivery of nucleic acids to bacteria in natural environments such as bodies of animals | YALE UNIVERSITY | 2003-08-26 | — | — | US | disclosed |
| US-6558954-B1 | Engineering disease resistant cells to be sensitive to therapeutic agents; obtain cells, transform with nucleotide sequences coding enzymatic polypeptide, express nucleotide sequences, monitor sensitivity to therapeutic agent | YALE UNIVERSITY | 2003-05-06 | — | — | US | disclosed |