SCHEMBL7179751

SCHEMBL7179751

COc1ccc(Br)cc1CN1CCN(C)C(C(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 10/20 0.56
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
KMT2A Q03164 1/20 0.51
CCR5 P51681 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6541045 0.92 TACR1 (0.54) TACR1KDM4EALDH1A1TDP1KMT2A
SCHEMBL6541473 0.88 TACR1 (0.69) TACR1
SCHEMBL6540987 0.87 TACR1 (0.49) TACR1KDM4EALDH1A1TDP1KMT2A
SCHEMBL6541053 0.87 TACR1 (0.53) TACR1KDM4EALDH1A1TDP1KMT2A
SCHEMBL6540941 0.87 TACR1 (0.56) TACR1KDM4EKMT2A
Hydrochloric Acid SCHEMBL6541642 0.85 TACR1 (0.57) TACR1KDM4E
Hydrochloric Acid SCHEMBL6541654 0.85 TACR1 (0.57) TACR1KDM4E
SCHEMBL6540907 0.85 TACR1 (0.54) TACR1
SCHEMBL6541291 0.84 TACR1 (0.50) TACR1KDM4ETDP1KMT2ALMNA
SCHEMBL6540454 0.83 TACR1 (0.72) TACR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294700-A2 BENZHYDRYL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-26 EP disclosed
WO-2002000631-A2 BENZHYDRYL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-03 WO disclosed