Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107460 | 0.87 | TLR7 (0.55) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6699331 | 0.86 | TLR7 (0.54) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL4330880 | 0.85 | TLR7 (0.59) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6730779 | 0.84 | TLR7 (0.52) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6695790 | 0.84 | TLR7 (0.51) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6694771 | 0.84 | TLR7 (0.51) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6104970 | 0.83 | TLR7 (0.51) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6702071 | 0.83 | TLR7 (0.50) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL22043512 | 0.82 | TLR7 (0.62) | TLR7ADORA2ALMNAPOLBHRH2 | |
| SCHEMBL6105495 | 0.82 | TLR7 (0.50) | TLR7ADORA2ALMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341789-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046189-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |