Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Letrazuril SCHEMBL466345 | 0.81 | MEN1 (0.83) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL10420836 | 0.78 | MEN1 (0.72) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL10421447 | 0.74 | MEN1 (0.65) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL9823618 | 0.74 | MEN1 (0.83) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| Diclazuril SCHEMBL126138 | 0.73 | MEN1 (1.00) | MEN1KMT2ANR1I2THRBTHRA | |
| SCHEMBL10403617 | 0.71 | KMT2A (0.78) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL10671723 | 0.71 | MEN1 (0.66) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL7919703 | 0.71 | MEN1 (0.86) | MEN1KMT2ANR1I2THRBTHRA | |
| SCHEMBL10420205 | 0.69 | MEN1 (0.82) | MEN1KMT2ANR1I2ALDH1A1THRB | |
| SCHEMBL10675273 | 0.68 | MEN1 (0.58) | MEN1KMT2ANR1I2THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302468-A1 | Processes and intermediates for manufacturing retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2003-04-16 | — | — | EP | disclosed |