SCHEMBL718052

SCHEMBL718052

COC(=O)C(C)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2279499 1.00
SCHEMBL3994151 1.00
Hydrochloric Acid SCHEMBL6045106 0.97
Hydrochloric Acid SCHEMBL6043688 0.97
Hydrochloric Acid SCHEMBL2115 0.97
SCHEMBL14076414 0.81 SMN1; SMN2 (0.37)
SCHEMBL21114362 0.81 GABRR1 (0.39)
SCHEMBL30910747 0.80
SCHEMBL3392469 0.80
SCHEMBL30910817 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103159660-B (2R)-1-(2-methyl-3-(methoxyl group (methyl) amino)-propiono) pyrrolidine-2-carboxylic acid and application thereof 天津市国际生物医药联合研究院 2016-07-06 CN claimed
CN-103159660-A (2R)-1-(2-methyl-3-(methoxy(methyl)amino)-propionyl)pyrrolidine-2-carboxylic acid and application thereof TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE 2013-06-19 CN claimed
US-20100063019-A1 Low Dose Estrogen Interrupted Hormone Replacement Therapy DURAMED PHARMACEUTICALS, INC. (US) 2010-03-11 US claimed
EP-1712227-A1 Amino diols useful in the treatment of Alzheimer's disease Elan Pharmaceuticals, Inc. (US) 2006-10-18 EP claimed
EP-1603549-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS Yu, Ruey J., Dr. (US) 2005-12-14 EP claimed
US-20040220264-A1 Bioavailability and improved delivery of acidic pharmaceutical drugs YU RUEY J 2004-11-04 US claimed
WO-2004082628-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS YU RUEY J (US) 2004-09-30 WO claimed
US-20040180867-A1 Low dose estrogen interrupted hormone replacement therapy DURAMED PHARMACEUTICALS, INC. 2004-09-16 US claimed
US-6747019-B2 MIXTURE OF ESTROGEN, PROGESTERONE; ALTERNATING DOSAGE JENCAP RESEARCH, LTD. (CA) 2004-06-08 US claimed
EP-0735819-B1 CRYPTOPHYCINS UNIV HAWAII (US) 2001-07-11 EP claimed
JP-H09510436-A 1997-10-21 JP claimed
EP-0735819-A4 NEW CRYPTOPHYCINS UNIV HAWAII (US) 1997-03-19 EP claimed
EP-0735819-A1 NEW CRYPTOPHYCINS UNIVERSITY OF HAWAII (US) 1996-10-09 EP claimed
WO-1995017093-A1 NEW CRYPTOPHYCINS UNIVERSITY OF HAWAII (US) 1995-06-29 WO claimed
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors KEZAR LIFE SCIENCES, INC. (US) 2026-04-14 US disclosed
EP-3765447-B1 TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS KEZAR LIFE SCIENCES (US) 2023-07-12 EP disclosed
WO-2023108036-A1 CANNABINOID RECEPTOR MODULATING COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-06-15 WO disclosed
EP-0219852-A2 Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for producing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 1987-04-29 EP disclosed
EP-0159708-A2 Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for produing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 1985-10-30 EP disclosed
US-4025550-A Derivatives of triiodo-aminobenzenecarboxylic acids and the preparation thereof CHEMIE LINZ AKTIENGESELLSCHAFT (OE) 1977-05-24 US disclosed