SCHEMBL7180838

SCHEMBL7180838

OOC1(c2ccccc2)CCCCC1.OOc1ccccc1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 0.47
SLC6A2 P23975 5/20 0.38
SLC6A4 P31645 5/20 0.38
HTR1A P08908 4/20 0.38
SLC6A3 Q01959 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTR1D P28221 2/20 0.35
HTR1B P28222 2/20 0.35
ADRA2A P08913 4/20 0.35
ADRA2B P18089 3/20 0.35
ADRA2C P18825 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
ADRA1A P35348 2/20 0.35
OPRM1 P35372 2/20 0.35
USP2 O75604 1/20 0.35
CHRM1 P11229 1/20 0.35
CYP2C9 P11712 1/20 0.35
DRD1 P21728 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159996 0.82 PTGDR2 (0.58) PTGDR2SLC6A2SLC6A4HTR1ASLC6A3
SCHEMBL42935 0.82 PTGDR2 (0.58) PTGDR2SLC6A2SLC6A4HTR1ASLC6A3
SCHEMBL2352902 0.82 PTGDR2 (0.58) PTGDR2SLC6A2SLC6A4HTR1ASLC6A3
SCHEMBL2352942 0.81 PTGDR2 (0.56) PTGDR2SLC6A2SLC6A4HTR1ASLC6A3
SCHEMBL32679684 0.79 AKR1C1 (0.45) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL32679674 0.79 AKR1C1 (0.45) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL556975 0.79 AKR1C1 (0.45) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL5160288 0.79 AKR1C1 (0.45) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL9997758 0.78 PTGDR2 (0.55) PTGDR2SLC6A2SLC6A4HTR1ASLC6A3
SCHEMBL16843098 0.77 AKR1C1 (0.47) SLC6A2SLC6A4SLC6A3DRD3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268417-A1 METHOD FOR PRODUCING AROMATIC ALCOHOLS, ESPECIALLY PHENOL Degussa AG (DE) 2003-01-02 EP disclosed
WO-2001074767-A1 METHOD FOR PRODUCING AROMATIC ALCOHOLS, ESPECIALLY PHENOL DEGUSSA AG (DE) 2001-10-11 WO disclosed