Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776243 | 0.87 | STAT3 (0.55) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL15236787 | 0.87 | STAT3 (0.73) | STAT3ATMKDM4EPOLBCYP19A1 | |
| SCHEMBL31556187 | 0.85 | ATM (0.68) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL31556190 | 0.85 | ATM (0.68) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL23913120 | 0.85 | ATM (0.68) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL10773782 | 0.83 | STAT3 (0.51) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL10343404 | 0.83 | ATM (0.70) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL30869991 | 0.83 | ATM (0.70) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL10774028 | 0.81 | STAT3 (0.53) | STAT3ATMKDM4ETUBB4ATUBB | |
| SCHEMBL10776111 | 0.81 | STAT3 (0.53) | STAT3ATMKDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056700-A4 | MEDICINAL USES OF PHENYLALKANOLS AND DERIVATES | UNIV SYDNEY (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1056700-A1 | MEDICINAL USES OF PHENYLALKANOLS AND DERIVATES | THE UNIVERSITY OF SYDNEY (AU) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999020589-A1 | MEDICINAL USES OF PHENYLALKANOLS AND DERIVATIVES | THE UNIVERSITY OF SYDNEY (AU) | 1999-04-29 | — | — | WO | disclosed |