Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.75 |
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740716 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL350393 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL1684008 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL27719663 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL7189299 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL10448536 | 0.95 | TSHR (0.84) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL349758 | 0.92 | TSHR (0.80) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL5316010 | 0.92 | TSHR (0.78) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| Heptanal SCHEMBL11259390 | 0.89 | TSHR (0.94) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| Pentanal SCHEMBL11434933 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562958-B1 | Nucleotide sequences coding polypeptide for use in the treatment and prevention of infections | GENOME THERAPEUTICS CORPORATION | 2003-05-13 | — | — | US | disclosed |