SCHEMBL7181287

SCHEMBL7181287

CCCCCCCC[Sn](Br)(Br)Br

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
DNM1 Q05193 7/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527771 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5897382 0.87
Water SCHEMBL5897582 0.84 TSHR (0.38) TSHRTHRBALDH1A1LMNA
SCHEMBL11692220 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7781168 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL10778594 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7454656 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1526875 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL11800780 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2049112 0.81 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed
EP-0510410-B1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE FIRESTONE INC (US) 1996-06-12 EP claimed
EP-0538789-B1 Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups BRIDGESTONE CORP (JP) 1995-12-13 EP claimed
EP-0543305-B1 Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds BRIDGESTONE CORP (JP) 1995-10-11 EP claimed
US-5254628-A Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from aromatic nitrile compounds BRIDGESTONE CORPORATION (JP) 1993-10-19 US claimed
US-5227431-A DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE BRIDGESTONE/FIRESTONE, INC. (US) 1993-07-13 US claimed
EP-0543305-A1 Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from fused-ring polynuclear aromatic compounds or aromatic nitrile compounds BRIDGESTONE CORPORATION (JP) 1993-05-26 EP claimed
US-5210144-A Polymers for tire tread BRIDGESTONE CORPORATION (JP) 1993-05-11 US claimed
EP-0538789-A1 Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups BRIDGESTONE CORPORATION (JP) 1993-04-28 EP claimed
EP-0510410-A1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE/FIRESTONE, INC. (US) 1992-10-28 EP claimed
US-4616069-A REACTING THE ALKALI METAL OR ALKALINE EARTH METAL TERMINATED POLYMER WITH TIN COMPOUND AND ORGANIC COMPOUND HAVING AMIDE OR THIOAMIDE LINKAGES NIPPON ZEON CO., LTD. (JP) 1986-10-07 US claimed
CN-108026205-B Process for producing modified solution-polymerized diene rubber for mixing silica and rubber composition 有限会社ETIC 2021-01-29 CN disclosed
EP-3351569-B1 METHOD FOR PRODUCING MODIFIED SOLUTION-POLYMERIZED DIENE RUBBER TO BE BLENDED WITH SILICA, AND RUBBER COMPOSITION CONTAINING SAME ETIC INC (JP) 2020-11-04 EP disclosed
US-10428161-B2 Method for producing modified solution-polymerized diene rubber to be blended with silica, and rubber composition containing same ERIC Inc. (JP) 2019-10-01 US disclosed
US-4248738-A COMPRISING A TUNGSTEN COMPLEX, A HALOGENATED PROMOTER AND A TIN PROMOTER PHILLIPS PETROLEUM COMPANY (US) 1981-02-03 US disclosed
US-4148814-A Process for preparing monohydrocarbyltin trihalides PENNWALT CORPORATION (US) 1979-04-10 US disclosed
US-4046791-A Method for producing monoalkyl-tin-trihalides CHUGOKU MARINE PAINTS, LTD. (JA) 1977-09-06 US disclosed