Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 7/20 | 0.64 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TLR2 | O60603 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | FABP4 | P15090 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexanoate SCHEMBL28861098 | 1.00 | AKR1B1 (0.67) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Azelaic Acid SCHEMBL29887189 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Octanedioate SCHEMBL30480273 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL28557502 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Sebacic Acid SCHEMBL2190152 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Adipic Acid SCHEMBL10398140 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL31718810 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Dodecanoate SCHEMBL31306310 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Decanoic Acid SCHEMBL31208552 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG | |
| Dodecanoate SCHEMBL31306299 | 0.98 | FFAR4 (0.69) | AKR1B1FFAR4FFAR1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119859258-A | Polyester amide material, and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119280474-A | Vitreous gel, and preparation method and application thereof | 湖南朗晶医疗科技有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119019657-A | Porous silicon dioxide in-situ polymerization modified polyester and preparation method thereof | 中国纺织科学研究院有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118308801-B | Light antistatic nylon hanging net and preparation method thereof | 江苏广立吊索具有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118108940-B | Nylon composite material and preparation method and application thereof | 广州仕天材料科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118308801-A | Light antistatic nylon hanging net and preparation method thereof | 江苏广立吊索具有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118126516-A | Polyphenylene sulfide/copolyamide composite material modified by grafted compatibilizer and flexibilizer and preparation method thereof | 宁波华腾首研新材料有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118108940-A | Nylon composite material and preparation method and application thereof | 广州仕天材料科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-116640438-A | Aging-resistant PA double-6 glass fiber reinforced material and granulation processing technology thereof | 安徽中纤新材料有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-115678271-B | Preparation method of bio-based polyamide plant dye masterbatch | 常州大学 | 2023-08-22 | — | — | CN | claimed |
| CN-103539936-A | Polyamide, synthesis method and application thereof, and polyamide product | KINGFA SCIENCE & TECHNOLOGY CO | 2014-01-29 | — | — | CN | claimed |
| CN-103539937-A | Polyamide, and synthesis method and application thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2014-01-29 | — | — | CN | claimed |
| CN-103539935-A | Polyamide, and synthesis method and application thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2014-01-29 | — | — | CN | claimed |
| CN-103450653-A | Efficient antistatic PC/ASA alloy and preparation method thereof | SHANGHAI KUMHO SUNNY PLASTICS | 2013-12-18 | — | — | CN | claimed |
| CN-103328539-A | Method for producing polyamide 66 | STAMICARBON BV DBA MT INNOVATION CT | 2013-09-25 | — | — | CN | claimed |
| CN-101899204-B | Antistatic PC/ASA alloy material and preparation method thereof | SHANGHAI KUMHO SUNNY PLASTICS | 2013-08-28 | — | — | CN | claimed |
| CN-102015842-A | Method for increasing the difference between the melting temperature and the crystallization temperature of a polyamide powder | ARKEMA FRANCE | 2011-04-13 | — | — | CN | claimed |
| CN-101899204-A | Antistatic PC/ASA alloy material and preparation method thereof | SHANGHAI KUMHO SUNNY PLASTICS | 2010-12-01 | — | — | CN | claimed |
| CN-1108330-C | Process and device for standardised continuous production of polyamides | POLYMER ENG GMBH (DE) | 2003-05-14 | — | — | CN | claimed |
| US-4248765-A | Surface polymerization on pigments for improved dispersibility | BASF WYANDOTTE CORPORATION (US) | 1981-02-03 | — | — | US | claimed |