⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932387 | 0.75 | — | — | |
| SCHEMBL197643 | 0.72 | — | — | |
| SCHEMBL2511823 | 0.72 | — | — | |
| SCHEMBL778652 | 0.72 | USP2 (0.44) | — | |
| SCHEMBL3215329 | 0.72 | USP2 (0.44) | — | |
| SCHEMBL16638881 | 0.71 | — | — | |
| SCHEMBL4809654 | 0.67 | — | — | |
| SCHEMBL9664977 | 0.67 | — | — | |
| SCHEMBL8629692 | 0.67 | — | — | |
| SCHEMBL6013346 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117554509-B | Method for detecting distribution and occupancy of cysteine-coupled ADC coupling sites and method for calculating drug-antibody ratio | 上海凯莱英生物技术有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-117554509-A | Method for detecting distribution and occupancy of cysteine-coupled ADC coupling sites and method for calculating drug-antibody ratio | 上海凯莱英生物技术有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-115372607-A | Phosphate buffer solution, labeling buffer solution and preparation method of alkaline phosphatase-antibody conjugate | 武汉生之源生物科技股份有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-110082441-B | Method and kit for detecting forbidden essences | 中国检验检疫科学研究院 | 2022-03-01 | — | — | CN | claimed |
| CN-111690499-A | Blending process of strong aromatic Chinese spirits | 湖北古襄阳酒业有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111072539-A | Simple and convenient preparation method of methyl thiomethanesulfonate | 北京工商大学 | 2020-04-28 | — | — | CN | claimed |
| EP-1651162-B1 | IMPROVED CYTOTOXIC AGENTS COMPRISING NEW MAYTANSINOIDS | IMMUNOGEN INC (US) | 2015-10-21 | — | — | EP | claimed |
| US-7473796-B2 | Maytansinoid intermediates: N-alkyl- or aryldithioalkanoylalanines and N-alkanoyl- or aroylthioalkanoylalanines, e.g., N-methyl-N-(4-methyl-4-methyldithio-1-oxopentyl)-alanine; optical isomers and racemic mixtures; preparations from isobutylene sulfide and acetonitrile, methyl methanethiosulfonate, etc. | IMMUNOGEN INC. (US) | 2009-01-06 | — | — | US | claimed |
| US-20070270585-A1 | Maytansinoid intermediates: N-alkyl- or aryldithioalkanoylalanines and N-alkanoyl- or aroylthioalkanoylalanines, e.g., N-methyl-N-(4-methyl-4-methyldithio-1-oxopentyl)-alanine; optical isomers and racemic mixtures; preparations from isobutylene sulfide and acetonitrile, methyl methanethiosulfonate, etc. | IMMUNOGEN, INC. (US) | 2007-11-22 | — | — | US | claimed |
| US-7276497-B2 | For therapy of tumors | IMMUNOGEN INC. | 2007-10-02 | — | — | US | claimed |
| EP-1651162-A2 | IMPROVED CYTOTOXIC AGENTS COMPRISING NEW MAYTANSINOIDS | Immunogen, Inc. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2004103272-A2 | IMPROVED CYTOTOXIC AGENTS COMPRISING NEW MAYTANSINOIDS | IMMUNOGEN, INC. (US) | 2004-12-02 | — | — | WO | claimed |
| US-20040235840-A1 | For therapy of tumors | IMMUNOGEN, INC. | 2004-11-25 | — | — | US | claimed |
| EP-1021555-A4 | STABILIZATION OF $i(HELICOBACTER) UREASE | ORAVAX MERIEUX CO (US) | 2003-01-08 | — | — | EP | claimed |
| EP-1021555-A1 | STABILIZATION OF $i(HELICOBACTER) UREASE | Oravax Merieux Co. (US) | 2000-07-26 | — | — | EP | claimed |
| US-5985631-A | STABILIZATION; PREVENT AGGREGATION | ORAVAX-MERIEUX CO. (US) | 1999-11-16 | — | — | US | claimed |
| WO-1999013097-A1 | STABILIZATION OF HELICOBACTER UREASE | ORAVAX MERIEUX CO. (US) | 1999-03-18 | — | — | WO | claimed |
| EP-0445365-A1 | Preparation of alkyl alkanethiolsulfonates | ATOCHEM NORTH AMERICA, INC. (US) | 1991-09-11 | — | — | EP | claimed |
| WO-1991011713-A1 | ARSENITE USED TO REVERSIBLY BLOCK STEROID BINDING TO GLUCOCORTICOID RECEPTORS IN THE PRESENCE OF OTHER STEROID RECEPTORS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-08-08 | — | — | WO | claimed |
| US-4992578-A | Preparation of alkyl alkanethiolsulfonates | ATOCHEM NORTH AMERICA, INC. (US) | 1991-02-12 | — | — | US | claimed |