Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047230 | 0.91 | ADORA2A (0.63) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL7185374 | 0.90 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5713454 | 0.89 | ADORA2A (0.59) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL3052290 | 0.89 | ADORA2A (0.65) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL28412423 | 0.88 | ADORA2A (0.68) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL28416866 | 0.88 | ADORA2A (0.68) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL3054173 | 0.87 | ADORA2A (0.74) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL3047856 | 0.87 | ADORA2A (0.69) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL3047910 | 0.87 | ADORA2A (0.58) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL5713516 | 0.86 | ADORA2A (0.64) | ADORA2AADORA1MEN1KMT2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521754-B2 | Such as N-4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-2-methyl-isoni cotinamide | HOFFMAN-LA ROCHE INC. | 2003-02-18 | — | — | US | disclosed |