Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831734 | 0.84 | CA12 (0.55) | POLBMCOLN3KMT2AMEN1ALDH1A1 | |
| SCHEMBL894793 | 0.80 | KMT2A (0.57) | POLBMCOLN3KMT2AMEN1ALDH1A1 | |
| SCHEMBL6534914 | 0.77 | KMT2A (0.57) | KMT2AMEN1ALDH1A1HTTCA2 | |
| SCHEMBL28468319 | 0.77 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HTTCYP1A2 | |
| SCHEMBL7330470 | 0.77 | KMT2A (0.56) | MCOLN3KMT2AMEN1HTTCA2 | |
| SCHEMBL2520150 | 0.76 | MEN1 (0.66) | MCOLN3KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5281106 | 0.76 | MAPT (0.62) | POLBKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3378430 | 0.76 | MCOLN3 (0.57) | POLBMCOLN3ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL17174225 | 0.75 | C5AR1 (0.57) | POLBMCOLN3KMT2AMEN1ALDH1A1 | |
| SCHEMBL6831970 | 0.75 | C5AR1 (0.71) | POLBMCOLN3ALDH1A1HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |