Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | IL2 | P60568 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24141032 | 0.85 | MAPT (0.84) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL23447711 | 0.84 | MAPT (0.82) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL5313393 | 0.83 | MAPT (0.75) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL30447521 | 0.83 | MAPT (0.75) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL5934086 | 0.82 | MEN1 (0.58) | MAPTKCNK3RXFP1LMNAEPAS1 | |
| SCHEMBL4683413 | 0.82 | KCNK3 (0.88) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL3033881 | 0.82 | MAPT (0.69) | MAPTKCNK3RXFP1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL29693050 | 0.81 | KCNK3 (0.86) | MAPTKCNK3RXFP1LMNAMEN1 | |
| SCHEMBL14083448 | 0.81 | TRPV1 (0.67) | MAPTKCNK3RXFP1MEN1KMT2A | |
| SCHEMBL7816780 | 0.80 | MEN1 (0.76) | MAPTKCNK3RXFP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |