Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284586 | 1.00 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL283348 | 1.00 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL30361229 | 1.00 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL283621 | 1.00 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL284374 | 1.00 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL284557 | 0.99 | GAA (0.41) | GAAKMT2AMEN1ALOX5ESR1 | |
| SCHEMBL283441 | 0.95 | GAA (0.42) | GAAKMT2AMEN1ALOX5CYP1A2 | |
| SCHEMBL578411 | 0.93 | GAA (0.47) | GAAKMT2AMEN1ALOX5CNR2 | |
| SCHEMBL191486 | 0.93 | GAA (0.47) | GAAKMT2AMEN1ALOX5CNR2 | |
| SCHEMBL284516 | 0.93 | GAA (0.47) | GAAKMT2AMEN1ALOX5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596796-B1 | Emulsion crude rubber, synthetic latex or natural rubber latex subject to oxidative, thermal, dynamic and/or light- induced degradation, and as stabilizer at least one compound of formula I | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |