SCHEMBL7182820

SCHEMBL7182820

CC1CCC(=O)C(=O)C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL634197 0.80
SCHEMBL23645791 0.80
SCHEMBL9388661 0.77 CYP3A4 (0.32)
SCHEMBL15657312 0.75 CRBN (0.35)
SCHEMBL2249255 0.73
SCHEMBL2478351 0.73
SCHEMBL2247916 0.73
SCHEMBL10863274 0.73
SCHEMBL2249250 0.73
SCHEMBL2478352 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
CN-1550482-A Process for manufacture of trans-(R,R)-actinol DSM IP资产公司 2004-12-01 CN disclosed
EP-1284950-A1 PROCESS FOR THE PRODUCTION OF 2,2,6-TRIMETHYLCYCLOHEXANE-1,4-DIONE Degussa AG (DE) 2003-02-26 EP disclosed
EP-0915076-B1 Process for the preparation of trans-(R,R)-actinol HOFFMANN LA ROCHE (CH) 2002-01-16 EP disclosed
WO-2001087811-A1 PROCESS FOR THE PRODUCTION OF 2,2,6-TRIMETHYLCYCLOHEXANE-1,4-DIONE DEGUSSA AG (DE) 2001-11-22 WO disclosed
US-6300509-B1 CATALYST FOR DIASTEREOSELECTIVE TRANSFER HYDROGENATION OF (R)-LEVODIONE TO TRANS-(R,R)-ACTINOL IN PRESENCE OF HYDROGEN DONOR, WHICH SIMULTANEOUSLY CAN BE USED AS SOLVENT ROCHE VITAMINS INC. 2001-10-09 US disclosed
US-6187961-B1 HYDROGENATING (R)-LEVODIONE IN PRESENCE OF HYDROGEN DONAR AND A SOLVENT OR IN PRESENCE OF HYDROGEN DONOR WHICH SIMULTANEOUSLY USED AS THE SOLVENT, AND AN AMINO-AMIDE-RUTHENIUM COMPLEX ROCHE VITAMINS INC. 2001-02-13 US disclosed
CN-1223998-A Process for producing trans- (R, R) -actinol HOFFMANN LA ROCHE (CH) 1999-07-28 CN disclosed
EP-0915076-A1 Process for the preparation of trans-(R,R)-actinol F. HOFFMANN-LA ROCHE AG (CH) 1999-05-12 EP disclosed