SCHEMBL718284

SCHEMBL718284

CCCCCNC(=O)CC

nearest known ligand 0.85

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.85
KMT2A Q03164 1/20 0.85
CASP2 P42575 1/20 0.68
NAAA Q02083 1/20 0.63
EPHX1 P07099 7/20 0.62
FAAH O00519 2/20 0.57
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3708747 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL2944555 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL10866304 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL4501660 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL8197425 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL8210316 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL8209020 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL10866272 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL1901704 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1
SCHEMBL5436704 0.98 MEN1 (0.81) MEN1KMT2ACASP2NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020119-A Process for preparing N- (2-substituted ethyl) amides and N-vinyl amides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-115260050-B Method for preparing 3-bromo-N-aryl propionamide by using NBS 常州大学 2023-08-22 CN claimed
CN-114736134-B (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2023-06-06 CN claimed
CN-114736134-A (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2022-07-12 CN claimed
WO-2022052456-A1 APPLICATION OF ESTER GROUP-CONTAINING AROMATIC PROPIONAMIDE COMPOUND AND METABOLITE THEREOF IN PREPARATION OF DRUG FOR TREATING HEART FAILURE 长春金赛药业有限责任公司 2022-03-17 WO claimed
WO-2020204548-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME 재단법인 의약바이오컨버젼스연구단 2020-10-08 WO claimed
EP-2276496-B1 THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION UNIV CALIFORNIA (US) 2019-07-10 EP claimed
US-9421241-B2 Therapeutic modulation of ocular surface lubrication THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-08-23 US claimed
US-20160015780-A1 Therapeutic Modulation of Ocular Surface Lubrication THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-01-21 US claimed
US-9138457-B2 Therapeutic modulation of ocular surface lubrication THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-09-22 US claimed
US-20120052077-A1 THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION LUBRIS LLC 2012-03-01 US claimed
EP-2381957-A2 THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION Singularis Inc. (US) 2011-11-02 EP claimed
US-7939521-B2 2-arylpropionic acid derivatives and pharmaceutical compositions containing them DompePHA.R.MA S.p.A. (IT) 2011-05-10 US claimed
US-20110070222-A1 Therapeutic Modulation of Ocular Surface Lubrication THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-03-24 US claimed
EP-2276496-A1 THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION The Regents of The University of California (US) 2011-01-26 EP claimed
WO-2010083239-A2 THERAPEUTIC MODULATION OF VAGINAL EPITHELIUM BOUNDARY LUBRICATION TRUITT EDWARD R III (US) 2010-07-22 WO claimed
WO-2009137602-A1 THERAPEUTIC MODULATION OF OCULAR SURFACE LUBRICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-11-12 WO claimed
EP-2038267-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE Novartis AG (CH) 2009-03-25 EP claimed
WO-2007115058-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE NOVARTIS AG (CH) 2007-10-11 WO claimed
CN-1148811-A Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions RHONE POULENC RORER PHARMA (US) 1997-04-30 CN claimed