⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888119 | 0.95 | — | — | |
| SCHEMBL8886891 | 0.85 | — | — | |
| SCHEMBL8887804 | 0.83 | — | — | |
| SCHEMBL8889333 | 0.81 | — | — | |
| SCHEMBL7175360 | 0.80 | — | — | |
| SCHEMBL8128666 | 0.79 | — | — | |
| SCHEMBL7203141 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL7183624 | 0.75 | — | — | |
| SCHEMBL8136114 | 0.74 | — | — | |
| SCHEMBL8888122 | 0.73 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758240-B1 | PHARMACEUTICAL FORMULATIONS CONTAINING A BETA-LACTAMASE INHIBITING PENEM IN COMBINATION WITH A BETA-LACTAM ANTIBIOTIC AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2003-10-29 | — | — | EP | disclosed |
| EP-0666862-B1 | 6-(SUBSTITUTED METHYLENE) PENEMS AND INTERMEDIATES | SMITHKLINE BEECHAM PLC (GB) | 2000-04-19 | — | — | EP | disclosed |