⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10802935 | 1.00 | — | — | |
| SCHEMBL11023508 | 0.82 | — | — | |
| SCHEMBL23462150 | 0.71 | — | — | |
| SCHEMBL21822072 | 0.71 | — | — | |
| SCHEMBL20838545 | 0.71 | — | — | |
| SCHEMBL23462080 | 0.71 | — | — | |
| SCHEMBL23462141 | 0.71 | — | — | |
| SCHEMBL23462252 | 0.71 | — | — | |
| SCHEMBL23461972 | 0.71 | — | — | |
| SCHEMBL23462034 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109152650-B | Minimally invasive methods and systems for hemostasis in a bleeding closed tissue volume | 普罗赛普特生物机器人公司 | 2021-10-26 | — | — | CN | disclosed |
| US-6630445-B2 | Unglycosylated recombinant human alpha-fetoprotein made in a prokaryote (e.g., E. coli) | MARTINEX R & D, INC. (CA) | 2003-10-07 | — | — | US | disclosed |
| US-6534479-B1 | Disclosed is a method of inhibiting a neoplasm in a mammal, the method includes administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein. | MARTINEX R & D INC. (CA) | 2003-03-18 | — | — | US | disclosed |
| US-20020155996-A1 | Recombinant alpha-fetoprotein for treating cancers | MERRIMACK PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| US-6416734-B1 | PROVIDING DETECTABLY-LABELED UNGLYCOSYLATED RECOMBINANT HUMAN ALPHA-FETOPROTEIN OR FRAGMENT THEREOF CAPABLE OF BINDING TO A HUMAN NEOPLASTIC CELL, IMAGING | MARTINEX R&D INC. (CA) | 2002-07-09 | — | — | US | disclosed |
| EP-0805687-A1 | RECOMBINANT HUMAN ALPHA-FETOPROTEIN AND USES THEREOF | MURGITA, Robert, A. (CA) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022787-A1 | RECOMBINANT HUMAN ALPHA-FETOPROTEIN AND USES THEREOF | MURGITA ROBERT A (CA) | 1996-08-01 | — | — | WO | disclosed |