Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183534 | 0.98 | HDAC1 (0.33) | HDAC1HDAC2HDAC8ACACBNR1H4 | |
| Lithium SCHEMBL7179682 | 0.90 | ACACB (0.34) | HDAC1HDAC2HDAC8ACACBSMN1; SMN2 | |
| SCHEMBL7179936 | 0.89 | SMN1; SMN2 (0.36) | HDAC1HDAC2HDAC8ACACBNR1H4 | |
| Lithium SCHEMBL7189334 | 0.87 | ACACB (0.34) | HDAC1HDAC2HDAC8ACACBSMN1; SMN2 | |
| SCHEMBL7179676 | 0.87 | ACACB (0.34) | HDAC1HDAC2HDAC8ACACBSMN1; SMN2 | |
| Lithium SCHEMBL7187691 | 0.86 | NR1H4 (0.39) | NR1H4 | |
| Lithium SCHEMBL7180737 | 0.85 | ACACB (0.33) | HDAC1HDAC2HDAC8ACACBSMN1; SMN2 | |
| SCHEMBL7189324 | 0.85 | ACACB (0.34) | HDAC1HDAC2HDAC8ACACBSMN1; SMN2 | |
| SCHEMBL7175539 | 0.84 | HDAC1 (0.31) | HDAC1HDAC2HDAC8 | |
| SCHEMBL7187681 | 0.84 | NR1H4 (0.39) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579663-B2 | Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-20020107413-A1 | Organometallic monoacylarylphosphines | WOLF JEAN-PIERRE (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6399805-B2 | SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | disclosed |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | CIBA SPECIALTY CHEMICALS CORP. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107413-A1 | Organometallic monoacylarylphosphines | CBR1, NAF1, DHCR24 | HDAC1 1556/4885HDAC2 2156/4885HDAC8 1695/4885 |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | NAF1, DHCR24, CBR1 | HDAC1 1870/4885HDAC2 1993/4885HDAC8 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.