Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806429 | 1.00 | ELANE (0.39) | ELANEPTPN1ABCG2CA2BCHE | |
| SCHEMBL7183322 | 0.90 | ELANE (0.42) | ELANEPTPN1ABCG2BCHE | |
| SCHEMBL7183316 | 0.90 | ELANE (0.42) | ELANEPTPN1ABCG2BCHE | |
| SCHEMBL7190380 | 0.89 | PTPN1 (0.46) | ELANEPTPN1 | |
| SCHEMBL7190378 | 0.89 | PTPN1 (0.46) | ELANEPTPN1 | |
| SCHEMBL7180278 | 0.89 | PTPN1 (0.43) | ELANEPTPN1ABCG2 | |
| SCHEMBL7180283 | 0.89 | PTPN1 (0.43) | ELANEPTPN1ABCG2 | |
| SCHEMBL7178939 | 0.87 | MAOB (0.42) | ELANEPTPN1ABCG2CYP1A1CYP1B1 | |
| SCHEMBL7178934 | 0.87 | MAOB (0.42) | ELANEPTPN1ABCG2CYP1A1CYP1B1 | |
| SCHEMBL7178711 | 0.87 | PPARG (0.40) | ELANEPTPN1ABCG2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |