Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761014 | 0.83 | PDE7A (0.63) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL7183456 | 0.82 | PDE7A (0.66) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL31457325 | 0.82 | PDE7A (0.66) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL709679 | 0.81 | GAA (0.59) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL7188810 | 0.81 | PDE7A (0.50) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL7185488 | 0.79 | TSHR (0.45) | TSHRGAAGLAPOLBMAPK1 | |
| SCHEMBL7189756 | 0.78 | TSHR (0.52) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL7193536 | 0.76 | PDE7A (0.56) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL177741 | 0.76 | PDE7A (0.52) | PDE7ATSHRGAAGLAPOLB | |
| SCHEMBL7189659 | 0.76 | TSHR (0.58) | PDE7ATSHRGAAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |