Ethylene

Ethylene

SCHEMBL7184474

C=C.C=C(C(=O)O)C(C)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
TET2 Q6N021 4/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC7A5 Q01650 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16662 0.97
SCHEMBL7116467 0.97
SCHEMBL31173032 0.97
SCHEMBL7750671 0.92 TP53 (0.45) TP53TET2TET3TET1LMNA
SCHEMBL9340609 0.89 TP53 (0.43) TP53TET2TET3TET1LMNA
Methacrylic Acid SCHEMBL8824607 0.89 TP53 (0.43) TP53TET2TET3TET1LMNA
Phosphoric Acid SCHEMBL1137774 0.87 TP53 (0.41) TP53TET2TET3TET1LMNA
Succinic Acid SCHEMBL15401966 0.85 EGLN1 (0.43) TP53TET2TET3LMNA
SCHEMBL6547254 0.81 TP53 (0.36) TP53HPGD
SCHEMBL7713687 0.81 TP53 (0.36) TP53TET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827995-B1 Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers AIR PROD & CHEM (US) 2003-11-12 EP disclosed
US-6280561-B1 Hot melt adhesives comprising low free monomer, low oligomer isocyanate prepolymers AIR PRODUCTS AND CHEMICALS, INC. 2001-08-28 US disclosed
EP-0827995-A2 Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-03-11 EP disclosed
EP-0092446-B1 THERMALLY CURABLE OLEFINIC POLYMERS AND MANUFACTURING METHOD FOR CURED SHAPED OBJECTS MADE THEREOF ELF ATOCHEM S.A. (FR) 1987-12-16 EP disclosed
EP-0092446-A1 Thermally curable olefinic polymers and manufacturing method for cured shaped objects made thereof ELF ATOCHEM S.A. (FR) 1983-10-26 EP disclosed