Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25981499 | 0.94 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1RECQL | |
| SCHEMBL7188869 | 0.85 | — | — | |
| SCHEMBL995832 | 0.83 | TSHR (0.61) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL19281377 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL10081322 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL5056126 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL4530697 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL2254699 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL2345504 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL17506460 | 0.81 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165464-B1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2003-08-20 | — | — | EP | disclosed |
| EP-1165464-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 Chemicals Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058241-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |