Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184981 | 1.00 | CYP1A1 (0.61) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL9115243 | 0.90 | CYP1A1 (0.69) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL9115237 | 0.90 | CYP1A1 (0.69) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL7185724 | 0.88 | CYP1A1 (0.62) | CYP1A1CYP1B1TNFRSF1AMAPTLMNA | |
| SCHEMBL7177347 | 0.88 | CYP1A1 (0.57) | CYP1A1CYP1B1TNFRSF1AMAPTLMNA | |
| SCHEMBL9115417 | 0.86 | CYP1A1 (0.71) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL7177114 | 0.86 | MAOB (0.66) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL7177119 | 0.86 | MAOB (0.66) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL9115423 | 0.86 | CYP1A1 (0.71) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT | |
| SCHEMBL7179900 | 0.85 | CYP1A1 (0.64) | CYP1A1CYP1B1TNFRSF1AMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |