Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174276 | 1.00 | HRH3 (0.59) | HRH3FAAHGAASMN1; SMN2KCNH2 | |
| SCHEMBL7178305 | 0.91 | HRH3 (0.58) | HRH3FAAH | |
| SCHEMBL5203689 | 0.91 | HRH3 (0.66) | HRH3 | |
| SCHEMBL5207591 | 0.91 | HRH3 (0.66) | HRH3 | |
| SCHEMBL7178404 | 0.90 | HRH3 (0.59) | HRH3GAASMN1; SMN2 | |
| SCHEMBL7178336 | 0.89 | HRH3 (0.65) | HRH3FAAHGAASMN1; SMN2KCNH2 | |
| SCHEMBL7179017 | 0.85 | HRH3 (0.58) | HRH3FAAHGAASMN1; SMN2KCNH2 | |
| SCHEMBL7173537 | 0.83 | HRH3 (0.61) | HRH3GAASMN1; SMN2KCNH2 | |
| SCHEMBL7192481 | 0.83 | HRH3 (0.64) | HRH3FAAHGAASMN1; SMN2KCNH2 | |
| SCHEMBL5203366 | 0.83 | HRH3 (0.69) | HRH3FAAHGAASMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311482-A2 | NON-IMIDAZOLE ARYLOXYPIPERIDINES AS H3 RECEPTOR LIGANDS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002012190-A2 | NON-IMIDAZOLE ARYLOXYPIPERIDINES AS H3 RECEPTOR LIGANDS | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2002-02-14 | — | — | WO | disclosed |